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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP45
All Species:
14.55
Human Site:
S599
Identified Species:
24.62
UniProt:
Q70EL2
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EL2
NP_001073950
814
91733
S599
G
K
H
L
R
S
Y
S
P
Q
N
A
F
Q
T
Chimpanzee
Pan troglodytes
XP_001139771
814
91702
S599
G
K
H
L
R
S
H
S
P
Q
N
A
F
Q
T
Rhesus Macaque
Macaca mulatta
XP_001085248
815
91829
S600
G
K
H
L
R
P
H
S
P
Q
N
A
F
Q
T
Dog
Lupus familis
XP_539054
796
87704
H591
D
A
F
Q
T
L
S
H
S
Y
V
T
A
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K387
813
90343
S598
G
K
H
T
R
L
H
S
A
Q
N
A
F
Q
T
Rat
Rattus norvegicus
Q2KJ09
826
93743
P603
I
L
N
D
S
H
S
P
A
L
K
V
Y
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506389
799
87920
S593
Q
H
A
F
Q
S
L
S
Q
S
Y
T
P
A
S
Chicken
Gallus gallus
O57429
357
40913
R153
E
K
S
R
Q
M
W
R
R
Y
Q
E
R
E
D
Frog
Xenopus laevis
Q6PAW2
901
101274
E604
I
E
V
N
K
T
P
E
R
T
A
G
S
G
G
Zebra Danio
Brachydanio rerio
A8HAL1
815
90431
D610
E
Y
T
V
V
N
R
D
P
E
L
A
F
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121285
844
94413
N613
S
P
D
V
P
S
I
N
F
N
S
V
I
S
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790411
1122
123641
T627
T
D
E
V
S
G
T
T
D
D
D
K
R
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPT5
1083
120752
R641
I
S
E
R
P
F
F
R
P
L
S
K
S
E
V
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
N268
K
E
V
S
R
A
N
N
K
Q
C
E
C
I
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.4
72.2
N.A.
77.4
38.7
N.A.
63.7
20.1
38.5
38
N.A.
N.A.
29.3
N.A.
29.9
Protein Similarity:
100
99.7
96.6
81.5
N.A.
85.3
59.6
N.A.
75.5
29.7
56.4
56.6
N.A.
N.A.
49.1
N.A.
45.3
P-Site Identity:
100
93.3
86.6
0
N.A.
73.3
0
N.A.
13.3
6.6
0
20
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
93.3
0
N.A.
80
20
N.A.
26.6
26.6
20
46.6
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
8
0
0
15
0
8
36
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% C
% Asp:
8
8
8
8
0
0
0
8
8
8
8
0
0
0
8
% D
% Glu:
15
15
15
0
0
0
0
8
0
8
0
15
0
22
0
% E
% Phe:
0
0
8
8
0
8
8
0
8
0
0
0
36
0
0
% F
% Gly:
29
0
0
0
0
8
0
0
0
0
0
8
0
8
15
% G
% His:
0
8
29
0
0
8
22
8
0
0
0
0
0
0
0
% H
% Ile:
22
0
0
0
0
0
8
0
0
0
0
0
8
8
0
% I
% Lys:
8
36
0
0
8
0
0
0
8
0
8
15
0
0
8
% K
% Leu:
0
8
0
22
0
15
8
0
0
15
8
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
8
8
15
0
8
29
0
0
0
0
% N
% Pro:
0
8
0
0
15
8
8
8
36
0
0
0
8
0
0
% P
% Gln:
8
0
0
8
15
0
0
0
8
36
8
0
0
29
0
% Q
% Arg:
0
0
0
15
36
0
8
15
15
0
0
0
15
8
8
% R
% Ser:
8
8
8
8
15
29
15
36
8
8
15
0
15
15
8
% S
% Thr:
8
0
8
8
8
8
8
8
0
8
0
15
0
8
29
% T
% Val:
0
0
15
22
8
0
0
0
0
0
8
15
0
0
22
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
0
0
15
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _